Common use

Fluconazole is an antifungal antibiotic that is used to treat fungal infections called candidiasis. This medication is prescribed for the treatment of infections such as vaginal, throat, and fungal infections, urinary tract infections, peritonitis, and pneumonia. Fluconazole works by killing sensitive fungi by interfering with the formation of the fungal cell membrane.

Dosage and direction

Take it orally once a day, with or without food, using the measuring spoon. Take it at the same time each day if you want to get the best result with a full glass of water. Fluconazole can make you feel better after 24 hours. However, your symptoms may go away completely after just a few days. If there is no change in your health after a few days, consult with your doctor immediately.

The dosage for adults varies depending on the type of infection and consists of the following:

1) Genital thrush – 150mg as a single dose
2) Mucosal thrush – the dose depends on where the infection is located, 50mg once daily during the month.
3) Fungal skin infections – 50mg once daily for 2-4 weeks.
4) Internal fungal infections – 400mg on the first day, then 200-400mg once daily for 6-8 weeks or longer if needed.
5) To prevent fungal infections – 50-400mg once daily while you are at risk of getting an infection.
6) To prevent infections caused by Cryptococcus from coming back – 100-200mg once daily indefinitely

The dosage for children aged 4 weeks to 15 years old also varies depending on the type of infection and consists of the following:

1) Mucosal infections – 3mg/kg once daily
2) Internal fungal infections – 6-12mg/kg once daily
3) Prevention of fungal infections – 3-12mg/kg once daily while at risk of getting an infection.

For children 2-4 weeks old, the dosage is the same as above but given once every 2 days, with a maximum dose of 12mg/kg every 2 days.

For children less than 2 weeks old, the dosage is the same as above but given once every 3 days, with a maximum dose of 12mg/kg every 3 days.

Please note that this instruction presented here is for review purposes only. It’s essential to consult with your doctor before using. This will help you achieve the best results.

Precautions

For vaginal yeast infections, doctors usually prescribe a single dose of Fluconazole. If the yeast infection does not improve after 5 days, contact your doctor as soon as possible. Be careful with this medication if your medical history includes liver disease or kidney disease. Although uncommon, this drug may make you dizzy, so be more attentive while driving or using machinery. Limit alcohol intake. Fluconazole should not be used during pregnancy, becoming pregnant, or lactating without a doctor’s advice. Do not use it before breastfeeding without a doctor’s advice.

Contraindications

Fluconazole is not allowed for people who are hypersensitive to Fluconazole or other antifungal azole preparations, such as clotrimazole, ketoconazole, itraconazole, and others. Fluconazole is also contraindicated in:

– Kidney and liver disorders;
– Cardiovascular diseases, including heart diseases (heart rate or rhythm disturbances);
– Low blood levels of calcium, magnesium, or potassium.

Possible side effects

Possible side effects of Fluconazole may include:
– An allergic reaction, such as hives, difficulty breathing, swelling of your face, lips, tongue, or throat.
– Other possible side effects include:
– Nausea
– Stomach pain
– Low fever
– Loss of appetite
– Dark urine
– Clay-colored stools
– Jaundice (yellowing of the skin or eyes)
– Fever, chills, body aches, flu symptoms
– Severe blistering, peeling, and red skin rash
– Easy bruising or bleeding
– Unusual weakness
– Seizure (convulsions)
– Mild nausea, vomiting, diarrhea, or upset stomach
– Headache
– Dizziness
– Unusual or unpleasant taste in your mouth
– Skin rash or itching.

If you experience any of these side effects, stop using Fluconazole and consult your doctor as soon as possible. Also, consult with your doctor about any side effect that seems unusual.

Drug interaction

Fluconazole may interact with various medications, including:
– Blood thinners like warfarin (Coumadin)
– Cyclosporine (Gengraf, Sandimmune, Neoral)
– Oral diabetes medicines like glipizide (Glucotrol), glyburide (Diabeta, Micronase, Glynase), tolbutamide (Orinase), tolazamide (Tolinase), chlorpropamide (Diabinese), and others
– Rifabutin (Mycobutin) or rifampin (Rifadin, Rifater, Rifamate, Rimactane)
– Sedatives like diazepam (Valium), lorazepam (Ativan), alprazolam (Xanax), or midazolam (Versed)
– Seizure medications like phenytoin (Dilantin) or valproic acid (Depakene)
– Tacrolimus (Prograf)
– Theophylline (Theo-Dur, Theolair, Theochron, Elixophyllin, Slo-Phyllin, and others).

Please note that the interaction between two medications does not always mean that you must stop taking one of them. It usually affects the effect of drugs, so consult with your doctor about how interactions are managed or should be managed.

Missed dose

If you forget to take your dose on time, please do so as soon as you remember. But do not take it if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usual dose the next day at the same regular time.

Overdose

Symptoms of Fluconazole overdose may include confusion or unusual thoughts or behavior. If you experience one of them, call your doctor immediately.

Storage

Store Fluconazole at room temperature between 59-77 degrees F (15-25 degrees C), away from light, moisture, children, and pets. Do not use it after the expiration date.

Disclaimer

We provide only general information about medications, which does not cover all directions, possible drug interactions, or precautions. The information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed upon with your healthcare adviser or the doctor in charge of the case. We disclaim the reliability of this information and any mistakes it may contain. We are not responsible for any direct, indirect, special, or other indirect damage resulting from any use of the information on this site and for the consequences of self-treatment.